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ALPHA:
ALitretinoin versus PUVA in severe chronic HAnd eczema trial

The ALPHA trial compares Alitretinoin and PUVA therapy in patients aged 18 years and over with severe hand eczema which is not controlled on a daily (regular) basis with prescription steroid creams. This is to find out which is the most effective treatment:

PUVA

Hands are soaked
in psoralen

Hands are exposed
to UV light

Alitretinoin

Tablet
treatment

Taken once
a day

Both are equally used by doctors in standard clinical practice, but there is no clear evidence indicating which is most effective in treating which type of hand eczema.

BBC Look North (Yorkshire) features Dr Miriam Wittmann discussing the ALPHA trial – click the link http://www.bbc.co.uk/programmes/p03tqv2c to watch the full programme. Here’s a shortened version of the video on the BBC Look North face book page.

 

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