The Method
In order to test the aims/goals of STATIC, we are testing two different ways of taking ibrutinib.
Participants of the trial will be randomly assigned to one of two treatment groups:
- Pausing Ibrutinib
Participants in this group take a scheduled break from ibrutinib, and only restart if their CLL gets worse. If restarting ibrutinib controls the CLL again, participants will take another break from treatment. - Continuous Ibrutinib
Participants in this group will take ibrutinib every day. Participants will continue ibrutinib without a break as long as they are benefitting from it.