For Patients
For Patients
Amitriptyline: A safe, effective, well-tolerated option for the management of Irritable Bowel Syndrome
Low-dose amitriptyline has been shown to help people with IBS. In the ATLANTIS trial, over 460 people with persistent IBS symptoms took either amitriptyline or a placebo tablet for IBS over 6 months and Amitriptyline was better than placebo. People taking amitriptyline reported improvements in their IBS symptoms, found the treatment acceptable and experienced few and manageable side-effects. They were able to adjust the dose to fit their changing IBS symptoms without repeated visits to their doctor. Talk to your doctor about amitriptyline for IBS.”
Trial Results
Patients Results Summary (.pdf)
Patients Results Summary – Large Print (.pdf)