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Diabetic foot ulcers are wounds on the feet that occur in people with diabetes, mainly due to nerve damage causing areas of high pressure when walking.
Most wounds have bacteria on their surface, and if there are enough bacteria this can cause infection. This is why it is important to keep wounds clean and dry. Areas of high pressure usually occur over a bony prominence, and if a wound in one of these areas is deep, then the bone at the bottom of the wound can also become infected, a condition called osteomyelitis.
We are looking to;
There is no standard way to diagnose a bone infection, and at the moment doctors and podiatrists use different ways to decide on the diagnosis. There are risks associated with missing the diagnosis, and studies suggest that it may therefore be over-diagnosed leading to unnecessary prolonged antibiotic courses in some people.
For those with high-risk clinical features for bone infection, i.e. those appearances of the wound which may make your treating clinician consider a diagnosis of bone infection, we are looking to get additional information over 3 phases of the study:
We hope that the results of the study will help change future guidelines and improve care and outcomes of patients with diabetic foot ulcers.
Please select the version which was used when you joined the study.
If you’re not sure which one you need, please contact the trial team at DOMINO-Patients@leeds.ac.uk
To update your contact details with us please click here.
If you no longer wish to receive updates about the study or a copy of the final study results please click here.